She conceded a goal on England's first shot of the game, which came in the 19th minute after an excellent cross from Beth Mead found Ellen White unmarked in the box.
With the eyes of the nation on her Tuesday, Naeher cemented her place in USA soccer lore with one huge save during the Americans' semifinal match against England.
There was an unwelcome surprise for England too with goalkeeper Karen Bardsley missing out with a hamstring injury and Carly Telford drafted in.
Alex Morgan celebrates with teammate Rose Lavelle after scoring her team's second goal during the 2019 World Cup France semifinals vs. England.
It seemed as if England had tied the match once more, but after a VAR review, White was ruled offside but the smallest of margins.
As if responding to a challenge, the US once more scored from aerial distribution, this time in the 31st minute.
Christen Press, who started in Rapinoe's place, made it 1-0 for the U.S.in the 10th minute before White got the equalizer nine minutes later.
U.S. Soccer did not give a reason for her absence.
The Americans held a 2-1 lead heading into halftime.
Alyssa Naeher faced enormous pressure and had big cleats to fill as she entered this Women's World Cup as the replacement for legendary goalkeeper Hope Solo.
England had shut out its last four opponents but the United States attacked early as expected - the Americans have scored within the first 15 minutes of all of their games in France.
With the US fully exploiting the space they were given in midfield, England were in danger of letting the game slip out of their control but against the run of play they leveled in superb style.
The frustration of missing a chance to level was evident when Millie Bright was awarded a red card in the dying minutes. Or both. Both the Netherlands and Sweden have scored more goals per match than England.
Japan fisherman catch first whales as commercial hunts resume
Astrid Fuchs of the Whale and Dolphin Conservation (WDC) said in December that Japan's decision was "devastating news" for whales. Director of marine conservation at the International Fund for Animal Welfare , Patrick Ramage, that the trade will soon die out.
Tetris Royale Is The Battle Royale Game That Nobody Expected
But if you are getting your vintage games confused, Tetris is the one where you stack awkwardly shaped blocks that fall at speed. This will be the debut title of a multiyear agreement between the two companies that will see the development of multiple games.