Journeys on the roads could take "a lot" longer and should ideally be avoided if possible, said Met Office meteorologist Alex Burkill.
"It's a case of normal wintry hazards that we would expect - snow, ice, frost are going to be quite prevalent over the next few days".
Snow and Ice warnings for Thursday between 1.00pm and Friday 9.00pm for East Midlands, East of England, London & South East England, North West England, South West England, Wales, West Midlands and Yorkshire & Humber.
Heavy snow has been forecast in parts of the county.
Four separate yellow weather warnings have been issued that cover most of the UK.
Weather warnings for snow and ice have been issued for large parts of the United Kingdom, with up to 10cm (4in) of snow expected to fall on higher ground as temperatures drop. Some snow showers are possible from 4pm until the evening here.
The Met Office says; "Showers will develop during Thursday night and continue into Friday morning falling as a mixture of rain, sleet and snow".
Cumbria Roads Police also urged people to slow down as it shared an image of a auto overturned between junctions 36 and 39 of the A6 near the village of Shap. North Yorkshire police told people to "keep an eye out for each other, especially elderly and vulnerable relatives, neighbours and friends".
'Snow amounts will vary markedly across England and Wales with many places seeing very little accumulating snow.
Sleet showers are also predicted for between 5pm and 7pm and after 11pm, while snow showers have been forecast for between 12am and 3am on Friday morning.
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