Compatriots Alisson Becker and Ederson are among the league's best goalkeepers, but it is Alisson who usually gets the nod for Brazil, and we are just siding with the Liverpool man too.
The Argentinian has scored in all six of his previous home Premier League matches for City against the Reds - in stark contrast to his record at Anfield where he has never found the net.
Spurs were defeated 3-1 by Wolves on Saturday to leave them nine points behind Liverpool, who thrashed Arsenal.
Guardiola has already labelled it a must-not-lose game for his team, stating the title race would be finished should City slip 10 points adrift.
"Everybody can make a mistake but what he has done after it, in the same game, where he could feel bad and guilty for the team... his reaction was outstanding".
The Citizens now find themselves seven points adrift of league-leaders Liverpool and many are dubbing the game as "make or break" for Pep Guardiola's side.
City are seven points behind Jurgen Klopp's unbeaten side after losing two matches before defeating Southampton. I'm a manager and to play these games, to see what we can do on the big stage with people in these stadiums, it's a dream to play these games. "We have made a lot of points". It's hard with the qualities all the teams have but it's just not important what happens.
For all their squad depth it is the one position in which they are wholly dependent on the 33-year-old, with an array of other midfield talent unable to play that role to the same standard.
"It's important for me because now I can make decisions in January".
City will need all hands on deck if they are to nullify Liverpool's attacking threat and the return of Fernandinho from a thigh injury for that victory over the Saints was a major boost.
This will be quite the duel as one of the world's best strikers comes up against arguably the world's best defender. Pep Guardiola's side looked to be turning things around with a 3-1 win over Southampton but Liverpool will be a completely different test, with the Spaniard admitting their opponents may be the best team in the world.
Kompany, though, called on his side to avenge a painful Champions League quarter-final exit to Liverpool last season.
United Kingdom viewers can watch Manchester City vs Liverpool on Sky Sports Main Event and Sky Sports Premier League, channels 401 and 402 respectively on Sky and channels 501 and 502 respectively for Virgin Media users. They will be brimming with confidence against a City side looking unusually vulnerable.
And Liverpool boss Klopp is hoping to welcome back the versatile Milner, who has been sidelined with a hamstring problem, for the trip to City. Our teams play. He beats me, I beat him.
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