"I know this has happened at Manchester United before, because I have sat in this chair as manager of Porto and of Real Madrid".
"That's football, we lost, but tomorrow is another day and Saturday is another match".
Paul Pogba, as in the goalless first leg three weeks ago, began on the bench and was introduced on the hour in place of Marouane Fellaini, with Mourinho risking the ire of those United fans who demand an attacking approach on home soil by starting the Belgian.
United finally worked a clear opening in the 38th minute, a powerful drive from Marouane Fellaini beaten away by Sergio Rico after Alexis Sanchez turned a one-two into the path of the Belgium worldwide, who was making his first start of 2018.
Jose Mourinho must pick up the pieces after Man United's Sevilla shambles
Pablo Sarabia fed Ben Yedder, who drilled an accurate low effort into the bottom right corner to break the deadlock, before adding a second from close range with United rocking.
It was United who started on the front foot, with Lukaku seeing two early chances go begging following some good link up play with Lingard. It would be naïve to think that they will not fight in this game.
Manchester United captain Michael Carrick has announced he will hang up his boots at the end of the current campaign after 12 trophy-laden seasons at Old Trafford.
"After 10 to 15 minutes, Sevilla has a good team and can hide the ball in midfield".
"But I believed in myself, believed in the team and we showed we are a great team".
But with Pogba and Juan Mata left on the bench until midway through the second half, United posed little threat to Sevilla and Ben Yedder's double proved enough to win the game, despite Romelu Lukaku's late strike.
But it was to little avail as United have now failed to reach the quarter-finals for four straight years.
Conspiracy theory about the biggest NCAA Tournament snubs
The two teams have already played once this season, with DePaul winning 111-108 in overtime in the second game of the season. The class of 2018, which includes Kyron Cartwright, Rodney Bullock, and Jalen Lindsey, have never missed an NCAA Tournament.
Sri Lanka can't stop India in Colombo
Raina's stay at the crease ended when he gave Nuwan Pradeep the charge but could only find Sri Lanka skipper Thisara Perera. Out of these 4, KL Rahul looks most likely to make a comeback into the team in place of the out of form Rishabh Pant.