Tottenham chairman Levy told journalists: "We believe there will be an National Football League team in the United Kingdom, and we want Tottenham to be the home of that team".
Game times will be announced at a later date but it's reasonable to expect that, for the first time since the International Series began in 2007, two teams with wining records could meet.
The Eagles, Seahawks and Titans all have never played in London before.
2018's other London games will take place on October 21 and 28, with the Philadelphia Eagles taking on the Jacksonville Jaguars and the Tennessee Titans taking on the Los Angeles Chargers, though which game happens on which date has yet to be decided.
The NFL has scheduled arguably its most impressive slate of London games yet in an announcement at Tottenham's new stadium.
The game will take place on October 14 at English Premier League side Tottenham Hotspur's new stadium during Week 6. It will be a Chargers home game played in Week 7 or Week 8.
The Jaguars are no strangers to London, owning a 3-2 record since first appearing in the International Series in 2013.
The most brutal stretch came in Weeks 2-4, when the Dolphins went to Los Angeles, New York and London for consecutive games.
Ticketing details will be announced by NFL UK on January 18.
To register for NFL London 2018 tickets all you need is your basic details and to state which game you're interested in attending. Additionally, fans can sign up at www.chargers.com/london for the latest information about the Chargers trip overseas to London.
Walmart to Raise Minimum US Wage to $11 an Hour
Walmart also said it would offer financial help to full-time hourly and salaried employees who are seeking to adopt children. Walmart said that the one-time bonus will be given to all eligible full and part-time hourly USA employees.