Andrea Ranocchia's failed clearance gave Crystal Palace's Wilfried Zaha an easy goal in the third minute, and the Tigers never recovered from having to play from behind the eight ball from nearly the beginning.
Hull still have one game left to play this season and this comes on home soil this Saturday when they take on Tottenham Hotspur, who have been edged out for the title for the second year running.
Hull City manager Marco Silva reacts after the match against Crystal Palace at Selhurst Park May 14, 2017. Therefore they will only be relegated if there is an unlikely swing in both points and goal difference.
Sam Allardyce admitted that survival was "a massive relief" after Crystal Palace ensured their Premier League safety with a 4-0 win that relegated Hull City.
Including defender Andrea Ranocchia, who set the tone for Hull's collapse after he got the very basics of defending wrong inside the opening three minutes.
Hull, which will finish 18th, had begun the season with only 13 fit senior players, without a permanent manager and amid widespread predictions of relegation. Silva was hired to stop the rot but the task was beyond the Portuguese coach.
Wilfried Zaha, Christian Benteke, Luka Milivojevic and Patrick van Aanholt scored as the south Londoners sent Hull back down the Championship and secured their Premier League survival for a fifth successive season.
"It's been a collective effort from everyone connected to the club; so congratulations to the players, backroom staff, club staff and definitely our supporters for their help in getting us over the line". "We'll regroup and come back fighting". "Now it is the moment to analyze".
Sam Allardyce has praised his Crystal Palace team for using nervous energy positively against Hull City at the weekend. It was really unlucky for West Ham, but it was really lucky from our position. That was one target I had in my career, and we tried to do our best.
"I think because of the run-in, the teams we had to play, this was the hardest and it means we haven't wasted the magnificent results we achieved in a short spell against Chelsea, Liverpool and Arsenal".
Only two matches remain in the 2016/17 Premier League season. That's something we'll discuss in the future.