The next round will see two radically different visions.
As Le Pen celebrated the highest-ever voting tally for her Front National party, candidates knocked out in the first round began to endorse Macron, who ended his insurgent campaign with a result that confounded expectations.
Le Pen, 48, has also touted her pledges to suspend the EU's open-border agreement on France's frontiers, and to expel foreigners who are on the watch lists of intelligence services, as the right response to a series of Islamist attacks in France.
Le Pen went on the offensive against Macron in her first public comments Monday.
With a slew of leaders from the right and the left rallying behind Macron, the odds are stacked against her.
Yesterday, Macron topped the first round of voting for president, winning 23.75 percent of the vote to Le Pen's 21.53 percent. "He needs to show that he can assume the great responsibility of a nation that is divided and convince the country that it can thrive in a globalised world".
Run-offs are not traditionally fertile territory for Le Pen's National Front.
Investors were also waiting to hear more about a "massive" USA tax package that President Donald Trump said is coming on Wednesday, which could revive the so-called "Trump trade" that started after his election in November, and which came on hopes that policies seen as pro-growth would swiftly pass Congress.
"Her radical views on immigration, the European Union and the euro should see a solid resistance from the majority of the population", said Ipek Ozkardeskaya, senior market analyst at LCG, in a note to clients.
Measures of expected volatility of the euro - driven to their highest in a year by nerves ahead of the vote - returned to relatively normal levels around 8.5 percent, pointing to a fall in concern over the prospects of a victory for anti-EU, anti-euro nationalist Marine Le Pen next month. "There is not one domain that he shows one ounce of patriotism", she said.
Investors have been assured by the long odds on a Le Pen presidency.
"There are not several Frances, there is one", Macron said.
"Macron has been by far the least divisive of the major candidates", Schmieding said. "That should enable him to attract extra support".
Macron's internal security programme calls for 10,000 more police officers, and 15,000 new prison places.
Still, Le Pen will argue that only she can bring real change to France.
The tweet like most of those posted under the hashtag appeared to be from leftist voters unhappy that neither Jean-Luc Melenchon or Benoit Hamon made the run off vote.
But that doesn't mean the former investment banker has been given a true mandate from voters.
Many voters said they would refuse to cast a ballot in the second round on May 7th because they did not want either Le Pen or Macron.
"The French have a very simple choice: either we continue on the road of total deregulation, without borders and without protection with the outcome of job losses overseas, unfair global competition, mass immigration and the free movement of terrorists. They can be in agreement with us", Steeve Brios, the mayor of Le Pen's northern bastion of Henin-Beaumont, told The Associated Press, adding that those far-left voters sought choices "outside the system".
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